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Rolf F Barth Selected Research

Neutron Capture Therapy

1/2018Boron delivery agents for neutron capture therapy of cancer.
12/2015Evaluation of TK1 targeting carboranyl thymidine analogs as potential delivery agents for neutron capture therapy of brain tumors.
1/2013Biodistribution and subcellular localization of an unnatural boron-containing amino acid (cis-ABCPC) by imaging secondary ion mass spectrometry for neutron capture therapy of melanomas and gliomas.
6/2011Convection enhanced delivery of carboranylporphyrins for neutron capture therapy of brain tumors.
12/2009Convection enhanced delivery of boronated EGF as a molecular targeting agent for neutron capture therapy of brain tumors.
12/2007Carboranyl thymidine analogues for neutron capture therapy.
1/2007Synthesis of cetuximab-immunoliposomes via a cholesterol-based membrane anchor for targeting of EGFR.
11/2004Boronated epidermal growth factor as a delivery agent for neutron capture therapy of EGF receptor positive gliomas.
11/2004Neutron capture therapy of epidermal growth factor (+) gliomas using boronated cetuximab (IMC-C225) as a delivery agent.
9/2004Boron-containing nucleosides as potential delivery agents for neutron capture therapy of brain tumors.
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Rolf F Barth Research Topics

Disease

51Neoplasms (Cancer)
06/2020 - 03/2002
46Glioma (Gliomas)
01/2022 - 06/2002
28Brain Neoplasms (Brain Tumor)
01/2022 - 03/2002
9Melanoma (Melanoma, Malignant)
01/2018 - 03/2002
6Glioblastoma (Glioblastoma Multiforme)
01/2022 - 06/2005
5Experimental Melanoma
01/2015 - 12/2011
3Gliosarcoma
01/2022 - 03/2003
2Carcinoma (Carcinomatosis)
07/2021 - 07/2003
1COVID-19
10/2021
1Sudden Death
05/2019
1Hemorrhagic Stroke
05/2019
1Stroke (Strokes)
05/2019
1Hemorrhage
05/2019
1Hypertension (High Blood Pressure)
05/2019
1Extramammary Paget Disease (Paget Disease, Extramammary)
01/2018
1Pathologic Constriction (Stenosis)
07/2017
1Atherosclerosis
07/2017
1Liver Neoplasms (Liver Cancer)
09/2016
1Head and Neck Neoplasms (Head and Neck Cancer)
08/2012
1Leukemia
01/2012
1Hypoxia (Hypoxemia)
07/2009
1Residual Neoplasm
07/2009
1Breast Neoplasms (Breast Cancer)
09/2005

Drug/Important Bio-Agent (IBA)

28BoronIBA
06/2020 - 03/2002
10ErbB Receptors (EGF Receptor)IBA
01/2016 - 06/2002
8Carboplatin (JM8)FDA LinkGeneric
09/2020 - 09/2007
8Epidermal Growth Factor (EGF)IBA
12/2009 - 06/2002
7thymidine kinase 1IBA
12/2015 - 09/2004
7Liposomes (Liposome)IBA
01/2012 - 05/2002
6ThymidineIBA
12/2015 - 09/2004
6Dendrimers (Dendrons)IBA
12/2009 - 11/2002
6Monoclonal AntibodiesIBA
02/2008 - 11/2004
6Cetuximab (Erbitux)FDA Link
02/2008 - 01/2004
5epidermal growth factor receptor VIIIIBA
02/2008 - 01/2004
4Cisplatin (Platino)FDA LinkGeneric
09/2020 - 07/2010
4SodiumIBA
12/2011 - 03/2003
4Folic Acid (Vitamin M)FDA LinkGeneric
07/2003 - 05/2002
3EnzymesIBA
12/2015 - 09/2004
3AcidsIBA
06/2014 - 12/2011
34-boronophenylalanineIBA
06/2014 - 12/2011
3Mannitol (Osmitrol)FDA LinkGeneric
01/2014 - 03/2002
3Biological ProductsIBA
09/2006 - 03/2003
2VaccinesIBA
10/2021 - 02/2005
2Peptides (Polypeptides)IBA
01/2016 - 02/2005
2NucleosidesIBA
07/2015 - 09/2004
2PlatinumIBA
01/2015 - 07/2010
2Amino AcidsFDA Link
01/2013 - 12/2011
2Pharmaceutical PreparationsIBA
12/2011 - 03/2003
2EpitopesIBA
06/2005 - 02/2005
1PoisonsIBA
05/2019
1Warfarin (Coumadin)FDA LinkGeneric
05/2019
1AnticoagulantsIBA
05/2019
1Phenobarbital (Luminal)FDA Link
07/2017
1AdipokinesIBA
07/2017
1MagnesiumIBA
03/2016
1Thymidine KinaseIBA
07/2015
1pyrimidineIBA
07/2015
1GadoliniumIBA
06/2015
1Levodopa (L Dopa)FDA LinkGeneric
06/2014
1Cyclic Amino AcidsIBA
06/2014
1antineoplaston A10 (A 10)IBA
02/2014
1Furosemide (Lasix)FDA LinkGeneric
01/2014
1Dexamethasone (Maxidex)FDA LinkGeneric
01/2014
1Amino Acid Transport Systems (Amino Acid Transporter)IBA
01/2013
1Protein Kinase CIBA
01/2012
1PorphyrinsIBA
06/2011
1A 7 (A-7)IBA
12/2009
1Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA
09/2009
1Methylnitrosourea (N-Methyl-N-nitrosourea)IBA
09/2009
1ferric oxide (iron oxide)IBA
07/2009
1Idoxuridine (Stoxil)FDA LinkGeneric
07/2009
1NitroimidazolesIBA
07/2009
1Contrast MediaIBA
07/2009
1ferumoxtran-10 (ultrasmall superparamagnetic iron oxide)IBA
07/2009
1CholesterolIBA
01/2007
1Boron CompoundsIBA
01/2007
1AnionsIBA
01/2007
1dodecaborateIBA
01/2007
1Methotrexate (Mexate)FDA LinkGeneric
01/2006
1Proteins (Proteins, Gene)FDA Link
09/2005
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2005
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
09/2005
1cyanine dye 5IBA
09/2005
1AntigensIBA
02/2005
1Lysine (L-Lysine)FDA Link
02/2005
1CytokinesIBA
02/2005
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
02/2005

Therapy/Procedure

27Boron Neutron Capture Therapy
06/2020 - 05/2002
16Neutron Capture Therapy
01/2018 - 03/2002
12Therapeutics
01/2022 - 01/2005
10Radiotherapy
09/2020 - 03/2003
3Injections
01/2022 - 11/2008
3Synchrotrons
06/2015 - 07/2009
1Pneumonectomy (Lung Volume Reduction)
07/2021
1Catheters
01/2020
1Laparotomy
09/2016
1Drug Therapy (Chemotherapy)
07/2010
1Euthanasia (Mercy Killing)
07/2009
1Nuclear Reactors
02/2008
1Chemoradiotherapy
09/2007